Section 1.2

Observational Studies vs. Designed Experiments

The "Golden Rule" of Statistics: Correlation does not apply Causation. But why? And how do we prove causation?

1

The Causation Barrier

We often find two variables that move together. Ice cream sales go up when shark attacks increase. Does ice cream cause shark attacks?

LogicLens: The Confounding Trap
Observational Study

We just watch. We record ice cream sales and shark attacks. We see a pattern (Association).

Result: Association ONLY
Designed Experiment

We interfere. We force one group to eat ice cream and ban another group from eating it.

Result: Causation Allowed

The Hidden "Z" Variable

In the shark example, there is a third variable (Lurking Variable) driving both:

Summer Heat

Heat → More Ice Cream
Heat → More Swimmers → More Sharks

2

Variable Dynamics

In any study, we are trying to see if one thing changes another. We give them distinct names.

The "Cause"

Explanatory Variable

The variable that we think explains the change. Also called the Independent Variable.

The "Effect"

Response Variable

The outcome we measure. Also called the Dependent Variable.

3

The "Hidden" Factors

ConceptDefinitionLogicLens Insight
Lurking VariableAn explanatory variable that was NOT considered in the study, but affects the Response.The "Ghost". It's not in your data set, but it's ruining your conclusion (e.g., "Summer Heat").
ConfoundingWhen the effects of two or more explanatory variables cannot be separated.The "Mix-up". Did the Fertilizer improve the plant, or was it the Extra Water? If you did both, they are confounded.
4

Taxonomy of Observational Studies

Cross-Sectional

Focus: The Present

Collecting data at a specific point in time. Like a 'Snapshot'. Fast but limited.

Case-Control

Focus: The Past

Retrospective. We look back at records. Good for rare diseases, but relies on memory/records.

Cohort

Focus: The Future

Prospective. We track a group over time. The most powerful observational method, but expensive.

5

The Gold Standard: Census

Why not just ask everyone?

A Census is a list of all individuals in a population along with certain characteristics.

Pros: 100% Accurate (No statistics needed)Cons: Expensive, Time-consuming, Impossible
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